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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
The above are the effects of Cialis (tadalafil).
  1. Taking Cialis topically: The medication is well-tolerated, but sexual dysfunction can occur, especially if the medication is taken in close contact with body fluids. This may cause fainting or bruising or delay treatment response.
  2. Taking Cialis with fat-soluble and fat-dense metabolites such as those for fats: Cialis with fat-soluble medications (e.g., those for blood pressure or cholesterol) is contraindicated in individuals witha kidney or liver disorder.
  3. : Though not a direct interaction, combining Cialis with Cialis-containing beverages can worsen side effects and increase the risk of heart attack or stroke in sensitive individuals.
Most side effects of Cialis (tadalafil) are mild to moderate in severity. These medications are not effective against sexually transmitted infections (STIs), but some are flagwasher unsafe.

C.

Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

Read more about Cialis's effects and how it can affect your health in more detail.Biggest neck pain in a few seconds. Biggest headache in a few seconds. This side effect is caused by Cialisautions, but it should not happen confusedingly. If you experience any of the following symptoms, contact your healthcare provider promptly:Biggest red spots on one side of the body.Small, slow, or fast can make you faint.
  • Pain in the stomach
  • Swelling of the hands, feet, or lips
  • Faintness
  • Swelling of the face, throat, or tongue

This is not a complete list of side effects. If you notice any changes in your condition, contact your healthcare provider promptly.

In addition, let your healthcare provider know if you are pregnant or plan to become pregnant. If you are, you should not take Cialis.

In the United States, if you have used Cialis without proper consultation, you should not take Cialis if you are pregnant. For the safety of your child, avoid using Cialis without proper consultation.

As with any drug product, there may be side effects. Generally, patients who experience side effects usually get them within 12 to 24 hours after taking Tadalafil. Side effects usually resolve on their own within 48 hours. Daily Tadalafil use is usually associated with lower incidents and severity of side effects compared to as-needed Tadalafil dosing.

Most common Tadalafil side effects

  • Headache
  • Indigestion
  • Back pain
  • Muscle pain
  • Flushing
  • Stuffy nose

Some more serious side effects have been reported. While rare, it is important to stop taking Tadalafil and contact a doctor right away if any of the following occur:

  • An erection will not go away (priapism). If you have an erection that lasts longer than 4 hours, get medical help right away. If not treated right away, priapism can permanently damage the penis.
  • Sudden vision loss in one or both eyes. Sudden vision loss can be a sign of a serious eye problem called non-arteritic anterior ischemic optic neuropath (NAION).
  • Sudden hearing decrease or hearing loss. Some may also have ringing in the ears (tinnitus) or dizziness.

For a complete list of possible side effects,.

Possible drug interactions

Some drugs/medications may interact with Tadalafil. You should not take Tadalafil if you are taking nitrates (such as nitroglycerin tablets or patches) because the combination of these with Tadalafil could significantly lower blood pressure and lead to fainting or even death. Additionally, do not take Tadalafil if you are taking Cisapride, other ED medications (e.g. Viagra), Adcirca, or Riociguat.

On your intake form, please be sure to provide AgelessRx with all medications, herbs, non-prescription drugs, or dietary supplements you use. Also be sure to report if you smoke, drink alcohol, or use illegal drugs, as some may interact with your medication.

For a complete list of possible drug interactions,.

Other important safety information

Patients who have a condition called “left ventricular outlet obstruction” from valvular problems or heart muscle enlargement may get side effects such as fainting or light-headedness. Because patients with recent heart attacks or stroke, heart pains (angina), heart failure, uncontrolled blood pressure or uncontrolled irregular heart beats, severe liver disease, and retinal eye problems have not been studied, Tadalafil (Cialis) is not recommended for these patients. There may be rare occurrences of priapism or painful, prolonged erections. This is a serious condition that requires immediate medical attention. Patients should seek prompt medical attention if their erection lasts longer than four hours.

After taking a single tablet, Tadalafil can remain in the body for up to two days. It can remain longer if patients have problems with their kidneys or liver, or they are taking certain other medications.

Note:All information included on this page is a summary. It may not cover all possible information. If you have questions about this medication, talk to a doctor, pharmacist, or healthcare provider.

Note: The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

  • Cialis (tadalafil) 5 mg, 10 mg, 20 mg
  • Cialis (tadalafil) 20 mg

Pregnancy and Lactation

Consult your doctor before taking Tadalafil if you are pregnant or breastfeeding. There may be changes in the position of the penis or heartbeat during pregnancy or breastfeeding. If you cannot get an erection, you should not take Tadalafil. The effects of Tadalafil have not been studied in pregnant or breastfeeding women.

Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

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What is Cialis?

Cialis is a prescription medication that’s been used for many years for sexual function conditions, such as erectile dysfunction (ED). ED is a medical condition when a man has trouble getting or keeping an erection. Cialis can make a big difference in ED, and it’s important to buy this medication as prescribed.

In some cases, Cialis can help treat arousal disorders like impotence. In these cases, Cialis can help treat low libido or a lack of sexual desire.

Cialis is also used to treat pulmonary arterial hypertension (PAH). PAH is a type of high blood pressure that’s high in pressure in the lungs. Cialis can help lower high blood pressure in the lungs by helping the blood pressure in your lungs decrease.

Cialis is very similar to the effects of monoamine oxidase (MAO) inhibitors such as isocarboxazid, linezolid, and phendamine. However, MAOIs can interact with Cialis, making it a less effective treatment.

How does Cialis work?

Cialis works by increasing the blood flow to your penis. When you take Cialis, it activates a chemical calledTadalafil, which enhances blood flow by relaxing the muscles in your penis.

Cialis helps you get and keep an erection. When you’re sexually aroused, your body releases a flood of nitric oxide, which stimulates the production of certain other chemicals in your body. This process increases the amount of amino acid in your body, which helps increase your blood flow.

Cialis can also help you lose any hair you have or use any facial flushing you’re used to. This is because Cialis can help you keep your face and other facial flushing as long as you don’t use or drink alcohol while taking Cialis.